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Research Activities

Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.

Research Activities at NCATS

Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.

Learn About NCATS Research Topics

Bridging Interventional Development Gaps (BrIDGs)

This in-house program helps researchers in advancing promising therapeutic agents through late-stage preclinical development to clinical testing.

Clinical and Translational Science Awards (CTSA) Program

This program funds a network of more than 60 leading medical institutions to improve the health of individuals and communities through research, resources and training.

Matrix Combination Screening

Our experts use matrix combination screening technology to quickly identify promising drug combinations with the most potential to help patients.

Platform Vector Gene Therapy (PaVe-GT)

Our pilot project is testing the feasibility of increasing the efficiency of gene therapy clinical trials by using the same gene delivery system and manufacturing methods for multiple gene therapies.

Rare Diseases Clinical Research Network (RDCRN)

We oversee this NIH-wide grant program that supports medical research on over 200 rare diseases through clinical studies, including collaborations, study enrollment and data sharing.

Therapeutics for Rare and Neglected Diseases (TRND)

Our experts help move new treatments for rare and neglected diseases through the later stages of drug development by collaborating with external scientists and companies.

Last updated on April 19, 2024