Research Activities
Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.
Research Activities at NCATS
Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.
A Specialized Platform for Innovative Research Exploration (ASPIRE)
Through this program, we are building an end-to-end solution for finding, designing and testing new molecules with the potential to become new treatments.
Antiviral Program for Pandemics (APP)
This multi-agency effort to develop safe and effective oral antiviral medications for future pandemics leverages our in-house drug discovery and development expertise and technologies.
Clinical and Translational Science Awards (CTSA) Program
This program funds a network of more than 60 leading medical institutions to improve the health of individuals and communities through research, resources and training.
Discovering New Therapeutic Uses for Existing Molecules (New Therapeutic Uses)
Awarded projects aim to streamline the process of discovering new treatments and cures for diseases by identifying new uses for existing assets that have already gone through significant development steps.
National COVID Cohort Collaborative (N3C)
We created and maintain this national resource of clinical and other data to answer critical research questions about COVID-19 health outcomes.
OpenDataPortal
Our OpenData Portal is an open and accessible platform for sharing COVID-19-related drug repurposing data and experiments involving approved drugs.
The Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®
As part of the NIH HEAL Initiative, we are applying our translational science approaches to accelerate the development of new treatments for opioid misuse, addiction and pain management.
Tissue Chip for Drug Screening
This program funds the development and testing of models built from human cells for predicting drug safety and toxicity before clinical testing in people.