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Research Activities

Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.

Research Activities at NCATS

Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.

Learn About NCATS Research Topics

3-D Tissue Bioprinting Program

Our scientists are creating and using 3-D printing techniques to make tissue models that closely resemble the complex structure and organization of our cells.

Antiviral Program for Pandemics (APP)

This multi-agency effort to develop safe and effective oral antiviral medications for future pandemics leverages our in-house drug discovery and development expertise and technologies.

Assay Development and Screening Technology (ADST)

Our scientists explore and develop new ways to quickly test and screen potential drug candidates, often in collaboration with disease foundations.

Bespoke Gene Therapy Consortium (BGTC)

We help lead this public-private partnership program that focuses on developing platforms and standards to speed the development and delivery of gene therapies for rare diseases.

Chemistry Technology

Our chemistry technology experts develop small molecules and screening methods that can be used by other scientists to drive innovations in therapeutic development.

Compound Management

Our compound management team uses sophisticated and automated techniques to supply chemicals for NCATS screening experiments to uncover new treatments for diseases.

Functional Genomics Lab

Our functional genomics experts work with collaborators from across NIH institutes and centers to design and use functional genomics technology to advance drug discovery and knowledge about health and disease.

Matrix Combination Screening

Our experts use matrix combination screening technology to quickly identify promising drug combinations with the most potential to help patients.

Stem Cell Translation Laboratory (SCTL)

Our experts develop methods and standards to use stem cell technology (using cells derived from skin or blood) to advance treatment approaches.

The Helping to End Addiction Long-termĀ® Initiative, or NIH HEAL InitiativeĀ®

As part of the NIH HEAL Initiative, we are applying our translational science approaches to accelerate the development of new treatments for opioid misuse, addiction and pain management.

Toxicology in the 21st Century (Tox21)

Our experts are part of this federal collaboration that aims to rapidly test whether substances are harmful to people.

Last updated on April 19, 2024