The Tissue Chip for Drug Screening program aims to develop bioengineered devices to improve the process of predicting whether drugs will be safe or toxic in humans. Learn more.
Explore this interactive model of the innovative developments from the NCATS-supported Tissue Chip for Drug Screening program.
Work with Us
The tissue chip program is designed to improve the way new drugs are developed and tested. Learn more about how you can join this effort.
Tissue Chip for Drug Screening
About Tissue Chip
Read more about the Tissue Chip program and its goal to create 3-D organs-on-chips.
Find more information about how the Tissue Chip program funds innovative research.
Tissue Chip Projects
Get details about active and completed tissue chip projects
Why Tissue Chip Matters
More than 30 percent of promising medications have failed in human clinical trials because they are determined to be toxic — despite promising pre-clinical studies in animal and cell models. Tissue chips are a newer, human cell–based approach to this challenge. The chip devices may enable scientists to predict more accurately how effective a therapeutic candidate would be in clinical studies.
Eliminating toxic and/or ineffective drugs earlier in the development process would save time and money. These human tissue chips also could teach us a great deal about disease progression, enabling researchers to better prevent, diagnose and treat disorders. Learn more about the Tissue Chip program.
Watch the Tissue Chip for Drug Screening video to learn more about the program.