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Therapeutics Discovery Funding Information

In May 2012, NIH launched the Therapeutics Discovery pilot program to match researchers with a selection of agents from industry to test ideas for new therapeutic uses. In Fiscal Year 2013, NCATS will provide up to $20 million for this program to fund two- to three-year staged, cooperative agreement research grants. If specific milestones are met, funded researchers will conduct pre-clinical validation and clinical feasibility studies in the first stage, and proof-of-concept clinical trials in the second stage. Some applications may request two-year support for proof-of-concept studies only.  

To solicit public input on the new program, NIH issued a Notice of Intent and a Request for Information. (See feedback on the RFI.) NIH issued three related funding announcements. The announcements encourage U.S. investigators to submit short applications about how they would explore specific hypotheses about how an agent available through the pilot might be useful in a specific disease area. View the library of agents.

Funding Announcements

These expired funding announcements include details on the application process, eligibility and associated timelines:

NOT-TR-12-010: Technical Assistance Webinar for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules Limited Competition RFA-TR-12-004 (UH2/UH3) and RFA-TR-12-005 (UH3)

NOT-TR-12-008: Clarification for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules

PAR-12-203: A Pre-application for the NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (X02)

RFA-TR-12-004: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH2/UH3)

RFA-TR-12-005: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH3)

Related Links

Contact

For more information about this program, contact Christine Colvis or Bonnie Dunn


Join the NCATS Listserv

Stay informed and keep updated about the latest news, funding announcements, and collaboration opportunities by signing up for one of NCATS' list servs. Join the NCATS announcement listserv for funding related news and subscribe to the e-newsletter listserv for the Center's latest news and announcements. 


Frequently Asked Questions


Technical Assistance Webinar

NCATS held a Therapeutics Discovery technical assistance webinar on Monday, June 25, 2012. Download the slides from this event.