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New Therapeutic Uses Funding Information

medical team sitting around table

NIH launched the New Therapeutic Uses pilot program in May 2012. By pairing researchers with a selection of industry-provided molecular compounds, the goal of this innovative program is to test ideas for new therapeutic uses, ultimately identifying promising new treatments for patients. 

In June 2013, NIH awarded $12.7 million to fund two-year and three-year cooperative agreements for nine projects in areas that include alcoholism, a type of progressive lung disease and cigarette smoking cessation. The NIH Common Fund is supporting the pilot phase of this NCATS-led program. If specific milestones are met, funded researchers will conduct pre-clinical validation, clinical feasibility studies, or proof-of-concept clinical trials to test whether selected compounds are effective against a previously unexplored disease target.

Funding Announcements

Current Opportunities

On January 27, 2014, NCATS issued the following request to industry for molecular compounds to use in next round of the New Therapeutic Uses program.

NOT-TR-14-001: Notice to Solicit Compounds for Inclusion in the NIH-Industry New Therapeutic Uses Program

Expired Announcements

These now-expired funding announcements include details on the application process, eligibility and associated timelines:

NOT-TR-12-010: Technical Assistance Webinar for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules Limited Competition RFA-TR-12-004 (UH2/UH3) and RFA-TR-12-005 (UH3)

NOT-TR-12-008: Clarification for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules

PAR-12-203: A Pre-application for the NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (X02)

RFA-TR-12-004: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH2/UH3)

RFA-TR-12-005: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH3)

Related Links

Contact

Christine Colvis, 301-451-3903


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