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Research

New Therapeutic Uses Funding Information

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NIH launched the New Therapeutic Uses collaborative program in May 2012. By pairing researchers with a selection of pharmaceutical industry agents, this innovative program aims to test ideas for new therapeutic uses, ultimately identifying promising new treatments for patients.

In June 2013 as part of a pilot initiative, NIH awarded $12.7 million to fund two-year and three-year cooperative agreements for nine projects in areas that include alcoholism, a type of progressive lung disease and tobacco cessation. If specific milestones are met, funded researchers will conduct pre-clinical validation, clinical feasibility studies or proof-of-concept clinical trials to test whether selected compounds are effective against a previously unexplored disease target.

In May 2014, NCATS issued four funding opportunities and provided information about partially developed therapeutic candidates (“agents”). For the first time in the program, the participating pharmaceutical companies have made available agents that are suitable for exploring pediatric indications.

Funding Announcements

Current Opportunities

There are no open NTU funding opportunities at this time. Information about future opportunities will appear on this page.

Expired Announcements

These now-expired funding announcements include details on the application process, eligibility and associated timelines for the program:

NOT-TR-15-008: Notice of Clarification Regarding Clinical Trial Documentation Requirements for New Therapeutic Uses Investigators 

PAR-14-210: Limited Competition for NIH-Industry Program: Discovering Pediatric New Therapeutic Uses for Existing Molecules (UH2/UH3)

PAR-14-211: Limited Competition for NIH-Industry Program: Discovering New Therapeutic Uses for Existing Molecules (UH3)

PAR-14-212: Limited Competition for NIH-Industry Program: Discovering New Therapeutic Uses for Existing Molecules (UH2/UH3)

PAR-14-213: Pre-application for the NIH-Industry Program: Discovering New Therapeutic Uses for Existing Molecules (X02)

NOT-TR-14-001: Notice to Solicit Compounds for Inclusion in the NIH-Industry New Therapeutic Uses Program

NOT-TR-12-010: Technical Assistance Webinar for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules Limited Competition RFA-TR-12-004 (UH2/UH3) and RFA-TR-12-005 (UH3)

NOT-TR-12-008: Clarification for the NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules

PAR-12-203: A Pre-application for the NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (X02)

RFA-TR-12-004: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH2/UH3)

RFA-TR-12-005: Limited Competition for NIH-Industry Pilot Program:  Discovering New Therapeutic Uses for Existing Molecules (UH3)

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Contact

Christine Colvis, 301-451-3903


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