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Industry Acquires First Drug Candidate from TRND Program

Red blood cells showing sickling from sickle cell disease.

On July 9, 2014, NIH announced that biopharmaceutical company Baxter International has acquired a drug candidate developed by NCATS' Therapeutics for Rare and Neglected Diseases (TRND) researchers and collaborators. The small molecule, Aes-103, is designed to treat sickle cell disease, a genetic blood disorder that affects millions worldwide, including approximately 100,000 people in the United States — among them, 1 in 500 African-Americans.

NIH News Release

NCATS Director’s Message

Baxter International News Release

TRND Aes-103 Project Page


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