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Schematic of META RNA profiling.

High-Throughput RNA Profiling via Up-Front Sample Parallelization

Analysis of gene expression within diverse specimens underpins our understanding of cellular physiology and disease. Discerning meaningful expression patterns within complex biological systems usually requires statistical comparisons in two dimensions: across multiple RNAs and multiple samples. Although mature technologies exist for highly parallel analysis in the first dimension, throughput efficiency remains limited in the second dimension.

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