Clinical and Translational Science Collaborative
Pamela B. Davis, M.D., Ph.D., Case Western Reserve University
The Clinical and Translational Science Collaborative, based at Case Western Reserve University, includes three hospital affiliates of the School of Medicine, the Cleveland Clinic, University Hospitals and MetroHealth Medical Center. Together, these hospitals cover 90 percent of the medical care delivered in the seven-county area surrounding Cleveland, Ohio, offering a wealth of clinical research opportunities. In addition, excellent programs based in the Frances Payne Bolton School of Nursing and the School of Dental Medicine, as well as those in the School of Medicine and its hospital affiliates reach into the community at many sites, some of which have become study sites in the CTSC. Together with the strong biomedical cores, the reach of these programs affords great opportunity for collaborative clinical research.
The Ohio State University Center for Clinical and Translational Science
Rebecca D. Jackson, M.D., Ph.D., Ohio State University
The Ohio State University (OSU) has established the Center for Clinical and Translational Science (CCTS) to improve the quality of care for all patients in the community by creating a transformative clinical and translational science discipline that is at the core of the OSU academic culture. It supports a robust and integrated partnership between the OSU and Nationwide Children's Hospital and links these sophisticated health care systems as a laboratory for biological, clinical and behavioral research. By also working through affiliated hospital networks, a primary care network and extension offices in all 88 counties in Ohio, CCTS accomplishes clinical and translational research through innovative collaboration with the community. As part of its community engagement plans, CCTS has selected the Appalachian region of Ohio as an area of emphasis — an area with some of the state's highest poverty rates. Expanding its community-based research programs to include unique partnerships with the Appalachia Community Cancer Network and Partners for Kids, a Nationwide Children's Hospital organization, provides clinical research opportunities to this rural community.
University of Cincinnati
James E. Heubi, M.D., University of Cincinnati
Joel Tsevat, M.D., University of Cincinnati
The Center for Clinical and Translational Science and Training (CCTST) is transforming the research environment among the University of Cincinnati and its affiliated partners in the community and industry. The CCTST will coordinate and plan the overall direction of the university's research infrastructure and training opportunities; serve investigators' needs from project concept to completion; optimize skills and foster career development of both new and experienced investigators; and ensure that community input informs research processes, and that the university's discoveries are translated to the community.
Through Research Central, researchers will have easy access to centralized study design, biostatistical, bioinformatics, regulatory and community engagement support. The new Pilot & Collaborative Studies core will expand the pilot funding program at Cincinnati Children's Hospital Medical Center to the entire university. Greatly expanded educational offerings, including a new Certificate in Clinical and Translational Research, will be developed, building on the success of the Dean's Scholars in Clinical Research, as well as a master's degree in Clinical and Translational Research program.
Through the community engagement program, CCTST will further bidirectional research linkages with the local community, breaking down bureaucratic barriers by creating Institutional Review Boards that can coordinate community-based research. Expanding services, such as nursing/coordinator support and sample processing provided by the existing General Clinical Research Center and the Cincinnati Department of Veterans Affairs Medical Center, will promote patient-oriented research for populations in the community.
New translational technologies, including proteomics, drug discovery, imaging, nanomedicine, gene transfer and stem cell biology, and translational and molecular disease modeling, will be made more accessible to researchers.