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Indiana Clinical and Translational Sciences Institute

Melissa Kacena, Ph.D., and team members

Melissa Kacena, Ph.D., right, associate professor of orthopaedic surgery at the Indiana University School of Medicine, works with members of her team to advance research funded by NIH and the U.S. Department of Defense on a compound that could act as a potential new, more effective treatment for broken bones. The project’s early phase received critical support from the Indiana CTSI. (Juan Guzman Photo)

Indianapolis, Indiana

Principal Investigator
Anantha Shekhar, M.D., Ph.D., Indiana University School of Medicine


The Indiana Clinical and Translational Sciences Institute (CTSI) — created in 2008 through the partnership of three research universities: Indiana University, Purdue University and the University of Notre Dame — has become an essential resource for the state’s biomedical initiatives. The Indiana CTSI is an integrated home for clinical and translational research, providing easily accessible resources, services and training in a collaborative, investigator-friendly environment. The Indiana CTSI aims to:

  • Implement a roadmap to build the ideal research environment for collaboration among participating universities, key health care providers, private sector and corporate entities, state and local agencies, and other partners.
  • Further develop the Indiana CTSI to support the careers and research projects of translational scientists and trainees through a streamlined structure, empowered leadership and administration, coordinated partner institution resources, robust informatics infrastructure, innovative project development teams, and continuous evaluation and process improvement.
  • Promote clinical and translational researchers’ use of the Project Assistance and Resources for Translational Scientists (PARTS) suite of new and established research support services and resources, a statewide network of technology cores, and coordinated human subject research services and facilities.
  • Enhance the statewide education and training of the clinical and translational research workforce through the Career development Education and Research Training (CERT) suite of programs and unique educational tools.

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