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Biology Group Leader, Division of Pre-Clinical Innovation
Posted June 8, 2015
NCATS seeks applications from qualified candidates to direct the RNAi Screening Core Facility, located within the Center’s intramural program and comprised of several biological scientists with informatics, automation, compound management and project management support. Facility staff collaborate with NIH intramural investigators to conduct genome-wide RNAi screening projects, including assay development, screening and validation, to understand functional biology and speed target discovery and validation. The biology group leader will be expected to develop methods that advance the science of RNAi screening and to perform education and outreach to increase awareness of the RNAi program tools and methods. The leader also will be expected to pursue new technologies for exploring gene function, including but not limited to CRISPR/Cas9 and related gene-editing approaches, as well as the interrogation of biological systems with annotated sets of perturbagens to advance the scientific breadth of the facility.
Each applicant must possess a doctoral degree in a relevant field and be a recognized expert and accomplished leader in the field. Applicants also must have a strong track record in the development of functional genomic and high-throughput cell-based assay systems and demonstrated experience in the management of a complex biomedical research operation. Experience in monitoring operations in matters related to personnel, budget, contracts, interagency agreements, and research grant writing and monitoring, including tracking requests for supplements, extensions and other related administrative issues, is required. Experience in screening druggable compound libraries and validation of gene expression profiling — using quantitative real-time polymerase chain reaction technology — is desirable. The ideal candidate will be highly innovative, interactive and collaborative and will serve as a spokesperson for the facility at NIH and at national and international forums.
The salary range is commensurate with experience and accomplishments; a full civil service package of benefits (including retirement, health, life and long-term care insurance, Thrift Savings Plan participation, etc.) is available.
Interested individuals should send a CV with bibliography, a vision statement for directing the biological research of the facility and the names of up to five references to NCATSRNAiRecruitment@mail.nih.gov.