NCATS is looking for innovative partners to join its dynamic team. Learn more about current job opportunities at NCATS or across NIH and the Department of Health and Human Services (HHS). NIH and HHS are Equal Opportunity Employers.
Postdoctoral Fellowship in Zellwegger Spectrum Disorders, Division of Pre-Clinical Innovation
NCATS seeks applications from qualified candidates with interest in the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD), a heterogeneous group of genetic disorders caused by mutations in PEX genes that are responsible for normal peroxisome assembly and functions, under the mentorship of Dr. Jim Inglese. The mission of the fellowship is to identify promising treatments that restore or functionally compensate for peroxisome dysfunction in individuals with PBD-ZSD. Candidates with a strong background in cell biology and biochemistry with proficiency in mammalian cell culture systems represented in their prior publications is required. Additionally, candidates should have a technical appreciation of laboratory automation, and have prior experience with large datasets. Experience with leukodystrophies and cell biology is a plus.
The post-doctoral fellow candidate will be responsible for leading a highly-collaborative, translational campaign that will focus on small-molecule screening of PBD-ZSD targets.The fellow will join the Assay Development and Screening Technology (ADST) Laboratory within the Division of Pre-Clinical Innovation, which has world-renowned capabilities in assay development, ultra-high-throughput screening, and chemistry, and discovers chemical probes of protein and cell functions. Successful candidates must be able to integrate multiple NIH resources (including iPSC generation and differentiation, genome editing, functional genomics, and clinical proteomics) to develop and interrogate physiological relevant assays.
Each applicant must possess a Ph.D. or be completing a Ph.D. program in bioengineering, pharmacology, cell biology or another relevant discipline. Ideally, candidates will be team players with high scientific standards and be able to work in an interactive, fast-paced environment.
Interested individuals should send send their CV including bibliography, and arrange for three letters of reference to be sent to: NCATS_ADSTpostdocs@mail.nih.gov. Review of applications will begin immediately and continue until positions are filled. View the full vacancy announcement. This postdoctoral fellowship is being funded by the Global Foundation for Peroxisomal Disorders (GFPD) and the Wynne Mateffy Research Foundation.
Stem Cell Scientist and Postdoctoral Positions, Division of Pre-Clinical Innovation
NCATS seeks applications from qualified candidates with expertise in the biology of human embryonic and induced pluripotent stem cells (iPSCs) to join the Center’s newly established stem cell program. Candidates with a strong background in cell, molecular and systems biology also are encouraged to apply.
The selected candidates will join a multidisciplinary team of innovative scientists with expertise in assay development, high-throughput and -content screening, compound management, automation engineering, bioinformatics, medicinal chemistry, and various “-omics” technologies. They will work in a highly creative environment, focusing on important aspects of human pluripotency and cellular differentiation using cutting-edge technologies (e.g., single-cell analysis, deep sequencing, automated cell culture, high-throughput electrophysiology). The selected candidates also will establish new standards, quality controls, improved differentiation protocols and other resources for the iPSC field. They will be responsible for conducting research and advancing specific programs in coordination with the stem cell team leader.
The ideal candidates will be expected to work independently as well-trained problem-solvers in pluripotent stem cell biology and iPSC technology. They will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. They also will draft technical reports, manuscripts and patent applications and present work internally and externally to consultants and collaborators as needed.
Each applicant must possess an advanced degree (M.D. and/or Ph.D.) in a relevant field. Exceptional candidates with master’s degrees and strong background in stem cell biology will be considered. Candidates with experience in drug discovery, cell and tissue engineering, cell signaling, or quantitative biology are encouraged to apply. The ideal candidates should be team players with high scientific standards and have the ability to work in an interactive, fast-paced environment. They must be self-motivated to learn new technologies and be familiar with the methods and concepts of stem cell biology and regenerative medicine.
Interested individuals should send a cover letter, curriculum vitae with bibliography and the contact information of at least three references to NCATSstemcellhiring@mail.nih.gov.
Review of applications will begin immediately and continue until positions are filled.